The Winding Road towards an Atropo?enantioselective ‘ARYNE Coupling’

نویسندگان

چکیده

For the first time, challenging atropo-enantioselective coupling of in-situ generated arynes and aryllithiums in presence a chiral ligand lithium was investigated. This preliminary study demonstrates feasibility this concept, by affording enantioenriched axially biaryls even case products showing high degree steric congestion around newly created aryl–aryl bond.

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ژورنال

عنوان ژورنال: European Journal of Organic Chemistry

سال: 2021

ISSN: ['1434-193X', '1099-0690']

DOI: https://doi.org/10.1002/ejoc.202100087